TOXICITY OF ABAMECTIN AND FIPRONIL ON SOME BIOCHEMICAL CHANGES IN FEMALE ALBINO RATS

Document Type : Research articles.

Authors

1 Plant Protection Department, Faculty of Agriculture Fayoum University, Egypt

2 Pathology Department, Faculty of Medicine, Fayoum University, Egypt

3 Plant Protection Department, Faculty of Agriculture Fayoum University, Egypt b

Abstract

Abamectin and fipronil are relatively new pesticides. LD50
values for abamectin and fipronil were 22.29 and 332.02 mg/kg body
weight respectively. It was cleared that abamectin fipronil female
albino rats. Toxicity of abamectin and fipronil were studied on certain
biochemical changes in female albino rats. Results showed that,
hemoglobin content, glutathione-S-transferase (GST), acetyl
cholinesterase and esterase content were significantly decreased for
rats treated with both pesticides in a concentration dependent. While
during recovery period (60 days) the results demons trated that
biochemical changes no improved for rats when compared to the
control groups. Our results, it can be concluded that abamectin and
fipronil have toxicity of hemoglobin content, glutathione-S-transferase
(GST), acetyl cholinesterase and esterase contents in female albino
rats.

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